Jeffrey E Herrick
Resistance training (RT), is a common and recommended strategy for weight management. Glucagon-like peptide-1 (GLP-1), is a rapid acting appetite control hormone. Purpose of this study was to determine if energy status prior to RT effects GLP-1 in females. Two randomized beverages were given prior to two RT days: 1) matched for RT calories (MC) and 2) no calories (NC). RT; 3 sets, 10 repetitions, 8 standard exercises at 70% 1-RM. Fasted blood was collected pre-beverage (PRE), 15-minutes post-beverage (POST), 5P, 15P, and 30P-minutes post-RT. Six females (age 21.8±2.6 yrs) completed the study. Differences from PRE to POST, 5p, 15P, 30P were measured with an ANOVA, and main effects analyzed with Cohen’s d effect size (d). NC promoted a significant reduction in GLP-1 at 15P, 30P RT (GLP-1 PRE 3.25 ±2.5, 15P 2.42 ±2.6, 30P2.46 ±2.1 ng/dL, p ≤ 0.05). There was no significant difference in GLP-1 in the matched calorie treatment (MC) at any time point in the study (PRE to POST, 5P, 15P & 30P). Results suggest, RT promotes a drop in GLP-1 at ~30 minutes following the exercise.