Lucia Gerzanic, Günter Schultes, Hans Kärcher and Doris Zebedin
Purpose: We describe successful treatment of a recurrent central giant cell granuloma (CGCG). This is a rare benign intraosseous lesion that occurs before age 30 and can quickly recur as a painless lesion of the mandible.Because of its aggressive growth and tendency to progress as well as its morphological similarity to a giant cell tumour, it justifies radical surgery.
Patients and methods: A female patient aged 18 years presented with a CGCG lesion in the mandible that recurred despite standard treatment with calcitonin nasal spray after enucleation of the initial lesion.
Results: The recurrence in the mandible required radical surgery and reconstruction with a microvascular iliac bone flap; there was no injury to cranial nerves and facial appearance was normal.
Conclusion: Radical surgical treatment of CGCG recurrence is the best option when calcitonin nasal spray fails to prevent recurrence.