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The Forensic Research/Reference on Genetics-knowledge Base, | 120910

法医病理学杂志

国际标准期刊号 - 2684-1312

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The Forensic Research/Reference on Genetics-knowledge Base, or FROG-kb, has Been Updated

Patrick Wilson

In the five years after the previous release, continued study into how the database may best assist forensics has led to considerable redesign of the database interface and functionality. The Forensic Resource/Reference on Genetics-knowledge base was first introduced in 2011. FROG-kb is a publicly available online interface that supports forensic practice and can be helpful for teaching and research. It was initially created as a prototype to support the forensic usage of Single Nucleotide Polymorphisms (SNPs). The web interface has been modified for simpler navigating across the many components based on information gained through its use. The website also offers new reference panels of SNPs with newly curated data, significant new documentation, and functional improvements. Single Nucleotide Polymorphisms (SNPs) are the emphasis of FROG-kb, which also supplies reference population data for various published panels of Ancestry Inference SNPs (AISNPs) and Individual Identification SNPs (IISNPs). FROG-kb computes Random Match Probabilities (RMP) and relative likelihoods of ancestry for a user-entered genotype profile (either totally or partially described) for each of the several marker panels using reference population data. There are available sample genotype profiles, and the User's Manual offers guidance for interpreting the calculations. The comprehensive instrument for supporting the use of SNPs in forensic practice and education is FROG-kb, which has substantial documentation and is constantly updated. Here is a description of the new FROG-kb along with examples and documentation outlining the outcomes of using i

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