Sanebela Olivia
Functional Mitral Regurgitation (FMR), which develops in Heart Failure (HF) settings as a result of changes in the geometry of the Left Ventricle (LV) and left atrium, is characterized by valve leaflets and chordae that are structurally normal. In this situation, FMR lowers life expectancy and raises mortality. There is still no universal cure for many patients with FMR, despite several medicinal and surgical treatments. FMR's pathophysiology is extremely intricate and involves numerous underlying pathways. Left ventricular dyssynchrony is a significant target for FMR therapy since it may contribute to the initiation and progression of FMR.