Gunawickrama SHNP, Hewavitharana KIG, Silva ARN, Nanayakkara PGCL, Gunawickrama KBS and Jayasekara JMKB
Objective: Risk factors among chronic kidney disease (CKD)/ chronic kidney disease of unknown aetiology (CKDu) patients were followed in Padaviya (PDV), and Girandurukotte/ Mahiyanganaya (GK/MH) of Sri Lanka, where CKDu was endemic. The studies profiled risk factor data pertaining to CKD and assessed risk factor association with renal dysfunction in the areas concerned. Methods: Data of initiation risk factors (IRF) that existed prior to diagnosis, progression risk factors and demography were collected in cross sectional studies at PDV, and GK/MH separately. Subject participation was volunteer and preceded informed consent. Control and CKD/CKDu groups were identified using serum creatinine based estimated glomerular filtration rate followed by verification of renal status with urine albumin to creatinine ratio obtained from spot samples. Data were analysed as compared to control with chi-square goodness of fit test and odds ratio. Results: Among IRF, both chi-square and odds ratio revealed (p