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Imeglimin: Therapeutic Option for Achieving Glycemic Control

Dr. Subhash Kumar

Imeglimin is a new class of drug which has introduced recently. The molecular mechanisms are unknown, although imeglimin improves insulin sensitivity in humans. Pre-clinical stu..查看更多»

研究文章

Dynamical downscaling of temperature variability over Tunisia:evaluation a 21-year-long simulation performed with the WRF model

Bilel Fathalli, Benjamin Pohl, Thierry Castel and Mohamed Jomâa Safi

This study evaluates the capabilities of the Weather Research and Forecasting (WRF) model to reproduce the space-time variability of near-surface air temperature over Tunisia. Do..查看更多»

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Role of Interleukin-6 in Diabetic Nephropathy

Spandana Vakapalli

Interleukin-6 (IL-6) was originally referred by diverse  names as interferons (Weissenbach et al., 1980; Zilberstein et al., 1986), 26K factor (Content et al., 1982; Haegem..查看更多»

案例报告

Bilateral Loss of Vision after Spinal Anaesthesia on a Dwarf Patient

Kassa MW, Shifa JZ, Bekele NA and Opondo PR

Achondroplasia is the most common form of dwarfism. Achondroplasia poses multiple anaesthetic challenges ranging from securing intravenous line, monitoring and drug dose calcula..查看更多»

研究文章

Implications of Androgen Receptor Hyperstimulation by the FKBP51 L119P Mutation: No Evidence for Early Emergence of L119P in Prostate Cancer

Bryan K. Ward*, Carmel Cluning, Ajanthy Arulpragasam, Jacqueline M. Bentel, David C. Chandler, Ronald J. Cohen, Gunnar Fischer, Michael R.Epis, Peter J. Leedman, Wayne D. Tilley Australian Prostate Cancer BioResource and Thomas Ratajczak

Objective: The immunophilin cochaperones, FKBP51 and FKBP52, have a modulating effect on steroid hormone receptors including the androgen receptor (AR). The dif..查看更多»

研究文章

The Relationship between Metabolic Syndrome and Markers of Cardiometabolic Disease among Canadian Adults

Darren R. Brenner, Paul Arora, Bibiana Garcia-Bailo, Howard Morrison, Ahmed El-Sohemy, Mohamed Karmali and Alaa Badawi

Background: The metabolic syndrome (MetS) is a well-established risk factor for cardiometabolic disease. However, the association between MetS, an..查看更多»