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Residual Microvascular Risk in Type 2 Diabetes in 2014: Is it Time for a Re-Think? A Perspective from the Residual Risk Reduction Initiative (R3i)

Michel P Hermans, Jean-Charles Fruchart, Jean Davignon, Khalid Al-Rubeaan, Pierre Amarenco

Microvascular complications associated with type 2 diabetes, including diabetic retinopathy, nephropathy and neuropathy, account for much of the societal burden of diabetes. Eve..查看更多»

研究文章

Changes in Serum Adipocytokines and Inflammatory Biomarkers Following One-Year of Exercise Training in Obese Adolescents

Aneta Gebala, Barbara Garanty-Bogacka, Monika Rac, Małgorzata Syrenicz, Mieczysław Walczak and Anhelli Syrenicz

Background: Obese individuals commonly demonstrate elevated levels of serum inflammatory markers and cell adhesion molecules. The later are known to be implicated in the pathoge..查看更多»

研究文章

Thrombospondin-1 Deficiency Exacerbates the Pathogenesis of Diabetic Retinopathy

Christine M Sorenson, Shoujian Wang, Robert Gendron, Hélène Paradis and Nader Sheibani

Diabetic retinopathy is a leading cause of blindness in the United States. Access to new animal models that exhibit retinal vasculopathies with short duration of diabetes, are v..查看更多»

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Developing New Molecules for the Treatment of Painful Diabetic Peripheral Neuropathy: Is it Feasible given the Magnitude of the Placebo Response in Proof of Concept Clinical Studies

Domenico Merante, George Skouteris and Rayaz Malik

Randomised, double blind, placebo controlled studies are necessary in neuropathic pain clinical research arena. Few drugs are approved for the indication of pai..查看更多»

研究文章

Ten Years of Activity at a Portuguese University Hospital Emergency Department: A Retrospective Observational Study

Humberto S Machado1, Catarina Nunes, António Marques, Isabel Almeida, António José Barros, Eurico Castro Alves, António Sousa Pereira, José Barros and Paulo Barbosa1

Background: Emergency department (ED) management relies on real-time information. Patient flow, length- of-stay (LOS), complaint related readmissions, and patie..查看更多»

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Liposuction Contouring After Head and Neck Free Flap Reconstruction

Amir E Ibrahim, Hamed Janom, Mohamad Raad

Resection of bulky head and neck tumors is typically followed by microvascular free flap reconstruction. The latter has shown an acceptable success rate but often requires a sec..查看更多»