国际在线医疗理事会(IOMC)| 医学研究

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研究文章

Possible Role of Sphingolipids in Developmental Programmed Cell Death of Petunia Petals

Domenico Prisa, Gianluca Burchi, Wouter G. van Doorn2

A type of programmed cell death (PCD) in animals is due to lysosomal membrane permeabilisation or rupture. One of the suggested reasons is sphingolipid accumulation in the membr..查看更多»

研究文章

Examination of Rare Variants in HNF4α in European Americans with Type 2 Diabetes

Jacklyn N. Hellwege, Pamela J. Hicks, Nicholette D. Palmer, Maggie C.Y. Ng, Barry I. Freedman and Donald W. Bowden

The hepatocyte nuclear factor 4-α (HNF4 α ) gene codes for a transcription factor which is responsible for regulating gene transcription in pancreatic beta cells, ..查看更多»

研究文章

A Clinical Phase II Study of Sorafenib in Advanced Hepatocellular Carcinoma

Hanan Shawky Gamal El Deen and Emad Abd-Elmongy Sadaka

Purpose:Sorafenib is an oral multikinase inhibitor of the vascular endothelial growth factor receptor, the platelet-derived growth factor receptor and Raf with ..查看更多»

研究文章

Elevated Angiotensin II in Rat Nodose Ganglia Primes Diabetes-Blunted Arterial Baroreflex Sensitivity: Involvement of NADPH Oxidase Derived Superoxide

Yu-Long Li

Clinical trials and experimental animal studies have confirmed the contribution of arterial baroreflex impairment in causing excess morbidity and mortality in type-1 diabetes. ..查看更多»

评论文章

The Interplay between the Androgen Receptor, Soluble Factors and Tumour Microenvironment

Vikash Reebye, Jeri Kim, Andrea Frilling, Joanna P. Nicholls, Nagy A. Habib and Paul J. Mintz

 Maintaining a balanced prostate microenvironment is pivotal for normal development and homeostasis of the prostate gland. This balance however is severely disrupted during..查看更多»