Christian T. Sheline
Zn2+ toxicity is implicated in pancreatic β-cell death that occurs secondarily to: streptozotocin exposure in vitro and both autoimmune attack or streptozotocin in vivo mod..查看更多»
Jonas Mathew
Type 1 diabetes is a chronic autoimmune disease characterized by the destruction of insulin-producing beta cells in the pancreas. It affects millions of individuals worldwide an..查看更多»
Liern JM, Codianni P, Mora F, Blumenthal L and Vallejo G
Background: Autosomal dominant polycystic disease (ADPKD) is characterized by the development of renal cysts. Objectives: 1) To assess the kidney and cyst volume growth in patients..查看更多»
Ammar Albourhi*, Fawzia Abdul Halim
Background: Type 1 diabetes is increasing by approximately 3% each year globally. Type 1 diabetes can manifest at any stage during the human life cycle, but par..查看更多»
Njeri LK and Eliud NM Njagi
Diabetes mellitus causes significant morbidity, mortality, and diabetes related complications. Conventional drugs are used in management of diabetes mellitus but are costly, are..查看更多»
Teayoun Kim, Lan He, Maria S. Johnson, Yan Li, Ling Zeng, Yishu Ding, Qinqiang Long, John F. Moore, Jon D. Sharer, Tim R. Nagy, Martin E. Young, Philip A. Wood and Qinglin Yang
Background: Carnitine Palmitoyl Transferase 1 (CPT1) is the rate-limiting enzyme governing long-chain fatty acid entry into mitochondria. CPT1 inhibitors have been developed and..查看更多»